Jean Théberge

Journal Articles

  1. Farag, A., Thompson, R.T., Thiessen, J.D., Butler, J., Prato, F.S., & J. Théberge. Assessment of a novel 32-channel phased array for cardiovascular hybrid PET/MRI imaging: MRI performance. Eur J Hybrid Imaging 3(13): 1-16 (2019) - [Published | Free Access]
  2. Harricharan, S., McKinnon, M., Tursich, M., Densmore, M., Frewen, P.A., Théberge, J., van der Kolk, B., & R.A. Lanius. Overlapping frontoparietal networks in response to oculomotion and traumatic autobiographical memory retrieval: implications for eye movement desensitization and reprocessing.. Eur J Psychotraumatology 10(1): 1586265 (2019) - [Published | PMID: 30949304]
  3. Nicholson, A.A., Densmore, M., McKinnon, M., Neufeld, R.W.J., Frewen, P.A., Théberge, J., Jetly, R. , Richardson, J., & R.A. Lanius. Machine learning multivariate pattern analysis predicts classification of posttraumatic autobiographical memory retrieval: implications for eye movement desensitization and reprocessing. Psychol Med (2018) - [Published | PMID: 30306886 | Free Access]
  4. Rabellino, D., Densmore, M., Théberge, J., McKinnon, M., & R.A. Lanius. The cerebellum after trauma: Resting-state functional connectivity of the cerebellum in posttraumatic stress disorder and its dissociative subtype. Human Brain Mapping (2018) - [EPub ahead of print | PMID: 29667267 | Free Access]
  5. Olivé, I., Densmore, M., Harricharan, S., Théberge, J., McKinnon, M., & R.A. Lanius. Superior colliculus resting state networks in post-traumatic stress disorder and its dissociative subtype. Human Brain Mapping 39(1): 563-574 (2018) - [Published | PMID: 29134717 | Free Access]
  6. Penner, J., Osuch, E.A., Schaefer, B., Théberge, J., Neufeld, R.W.J., Menon, R.S., Rajakumar, N., & P.C. Williamson. Higher order thalamic nuclei resting network connectivity in early schizophrenia and major depressive disorder.. Psychiatry Res Neuroimaging 272: 7-16 (2018) - [Published | PMID: 29247717 | Free Access]
  7. Taylor, R., Osuch, E.A., Schaefer, B., Rajakumar, N., Neufeld, R.W.J., Théberge, J., & P.C. Williamson. Neurometabolic abnormalities in schizophrenia and depression observed with magnetic resonance spectroscopy at 7 T. Br J Psychiatry 3(1): 6-11 (2017) - [Published | PMID: 28243459 | Free Access]
  8. Dempster, K., Norman, R., Théberge, J., Densmore, M., Schaefer, B., & P.C. Williamson. Cognitive performance is associated with gray matter decline in first-episode psychosis. Psychiatry Res Neuroimaging 264: 46-51 (2017) - [Published | PMID: 28458083 | Free Access]
  9. Rabellino, D., Siegle, G., Frewen, P.A., Densmore, M., Neufeld, R.W.J., Théberge, J., McKinnon, M., & R.A. Lanius. Neural correlates of heart rate variability in PTSD during sub- and supraliminal processing of trauma-related cues. Human Brain Mapping 38(10): 4898-4907 (2017) - [Published | PMID: 28714594 | Free Access]
  10. Nicholson, A.A., Harricharan, S., McKinnon, M., Densmore, M., Neufeld, R.W.J., Théberge, J., Jetly, R. , Spiegel, D., & R.A. Lanius. Dynamic causal modeling in PTSD and its dissociative subtype: Bottom-up versus top-down processing within fear and emotion regulation circuitry. Human Brain Mapping 38(11): 5551-5561 (2017) - [Published | PMID: 28836726 | Free Access]
  11. Harricharan, S., Nicholson, A.A., Densmore, M., Théberge, J., McKinnon, M., Neufeld, R.W.J., & R.A. Lanius. Sensory overload and imbalance: Resting-state vestibular connectivity in PTSD and its dissociative subtype. Neuropsychologia 106: 169-178 (2017) - [Published | PMID: 28911803 | Free Access]
  12. Nicholson, A.A., Rabellino, D., Densmore, M., Frewen, P.A., Kluetsch, R., Schmahl, C., Théberge, J., Neufeld, R.W.J., McKinnon, M., Jetly, R. , & R.A. Lanius. The neurobiology of emotion regulation in posttraumatic stress disorder: Amygdala downregulation via real-time fMRI neurofeedback. Human Brain Mapping 38(1): 541-560 (2017) - [Published | PMID: 27647695 | Free Access]
  13. Ros, T., Frewen, P.A., Théberge, J., Kluetsch, R., Mueller, A., Candrian, G. , Jetly, R. , Vuilleumier, P., & R.A. Lanius. Neurofeedback tunes long-range temporal correlations in spontaneous brain activity. Cereb Cortex 27(10): 4911-4922 (2017) - [Published | PMID: 27620975 | Free Access]
  14. Osuch, E.A., Théberge, J., Neufeld, R.W.J., Mitchell, D.G., Williamson, P.C., & R.C. Gardner . Depression, marijuana use and early-onset marijuana use conferred unique effects on neural connectivity and cognition. Acta Psychiatr Scand 134(5): 399-409 (2016) - [Published]
  15. Densmore, M., Frewen, P.A., McKinnon, M., Théberge, J., Nicholson, A.A., & R.A. Lanius. Desynchronization of autonomic response and central autonomic network connectivity in posttraumatic stress disorder. Human Brain Mapping 38(1): 27-40 (2016) - [Published | PMID: 27647521]
  16. Nicholson, A.A., Ros, T., Frewen, P.A., Densmore, M., Théberge, J., Kluetsch, R., Jetly, R. , & R.A. Lanius. Alpha oscillation neurofeedback modulates amygdala complex connectivity and arousal in posttraumatic stress disorder. NeuroImage Clin 12: 506-516 (2016) - [Published | PMID: 27672554]
  17. Taylor, R., Théberge, J., Williamson, P.C., Densmore, M., & R.W.J. Neufeld. ACC Neuro-over-Connectivity Is Associated with Mathematically Modeled Additional Encoding Operations of Schizophrenia Stroop-Task Performance. Front Psychol. 7: 1295 (2016) - [Published | PMID: 27695425]
  18. Harricharan, S., Rabellino, D., Frewen, P.A., Densmore, M., Théberge, J., McKinnon, M., Schore, A., & R.A. Lanius. fMRI functional connectivity of the periaqueductal gray in PTSD and its dissociative subtype. Brain Behav 6(12): (2016) - [Published | PMID: 28032002 | Free Access]
  19. Taylor, R., Théberge, J., Williamson, P.C., Densmore, M., & R.W.J. Neufeld. ACC Neuro-over-Connectivity Is Associated with Mathematically Modeled Additional Encoding Operations of Schizophrenia Stroop-Task Performance . Front Psychol. 7(1295): 1-23 (2016) - [Published | PMID: 27695425 | Free Access]
  20. Nicholson, A.A., Ros, T., Frewen, P.A., Densmore, M., Théberge, J., Kluetsch, R., & R.A. Lanius. Alpha oscillation neurofeedback modulates amygdala complex connectivity and arousal in posttraumatic stress disorder. NeuroImage Clin (2016) - [Accepted | Free Access]
  21. Penner, J., Ford, K.A., Taylor, R., Schaefer, B., Théberge, J., Neufeld, R.W.J., Osuch, E.A., Menon, R.S., Rajakumar, N., Allman, J.M., & P.C. Williamson. Medial prefrontal and anterior insular connectivity in early schizophrenia and major depressive disorder: a resting functional MRI evaluation of large-scale brain network models. Front Hum Neurosci. 10: 132 (2016) - [Published | PMID: 27064387]
  22. Nicholson, A.A., Sapru, I., Densmore, M., Frewen, P.A., Neufeld, R.W.J., Théberge, J., McKinnon, M., & R.A. Lanius. Unique insula subregion resting-state functional connectivity with amygdala complexes in posttraumatic stress disorder and its dissociative subtype. Psychiatry Res Neuroimaging 250: 61-72 (2016) - [Published | PMID: 27042977]
  23. Jie, N.F., Zhu, M.H., Ma, X.Y., Osuch, E.A., Wammes, M., Théberge, J., Li, H.D., Zhang, Y., Jiang, T.Z., Sui, J. , & V.D. Calhoun. Discriminating bipolar disorder from major depression based on SVM-FoBa: Efficient feature selection with multimodal brain imaging data. IEEE Trans Auton Ment Dev 7(4): 320-331 (2015) - [Published | PMID: 268588825]
  24. Rabellino, D., Densmore, M., Frewen, P.A., Théberge, J., & R.A. Lanius. The innate alarm circuit in post-traumatic stress disorder: Conscious and subconscious processing of fear- and trauma-related cues. Psychiatry Res Neuroimaging 248: 142-150 (2015) - [Published | PMID: 26749205]
  25. Daniels, J.K., Frewen, P.A., Théberge, J., & R.A. Lanius. Structural brain aberrations associated with the dissociative subtype of post-traumatic stress disorder. Acta Psychiatr Scand 133(3): 232-240 (2015) - [Published | PMID: 26138235]
  26. Taylor, R., Neufeld, R.W.J., Schaefer, B., Densmore, M., Rajakumar, N., Osuch, E.A., Williamson, P.C., & J. Théberge. Functional magnetic resonance spectroscopy of glutamate and glutamine in schizophrenia and major depressive disorder: anterior cingulate activity during a color-word Stroop task. npj Schizophrenia 1: 15028 (2015) - [Published | Free Access]
  27. Dempster, K., Norman, R., Théberge, J., Densmore, M., Schaefer, B., & P.C. Williamson. Glutamatergic Metabolite Correlation with Neuropsychological Tests in First Episode Schizophrenia. Psychiatry Res 233: 180-185 (2015) - [Published]
  28. Rabellino, D., Tursich, M., Frewen, P.A., Daniels, J.K., Densmore, M., Théberge, J., & R.A. Lanius. Intrinsic Connectivity Networks in post-traumatic stress disorder during sub- and supraliminal processing of threat-related stimuli. Acta Psychiatr Scand (2015) - [EPub ahead of print | PMID: 25865357]
  29. Steuwe, C., Daniels, J.K., Frewen, P.A., Densmore, M., Théberge, J., & R.A. Lanius. Effect of direct eye contact in women with PTSD related to interpersonal trauma: Psychophysiological interaction analysis of connectivity of an innate alarm system.. Psychiatry Res 232: 162-167 (2015) - [Published | PMID: 25862529]
  30. Nicholson, A.A., Densmore, M., Frewen, P.A., Théberge, J., Neufeld, R.W.J., McKinnon, M., & R.A. Lanius. The Dissociative Subtype of Posttraumatic Stress Disorder: Unique Resting-State Functional Connectivity of Basolateral and Centromedial Amygdala Complexes. Neuropsychopharmacology (2015) - [EPub ahead of print | PMID: 25790021]
  31. Taylor, R., Schaefer, B., Densmore, M., Neufeld, R.W.J., Rajakumar, N., Williamson, P.C., & J. Théberge. "Increased Glutamate Observed Upon Functional Activation in the Anterior Cingulate Cortex Using the Stroop Task and Functional Spectroscopy". Neuroreport 26(3): 107-112 (2015) - [Published | PMID: 25536234 | Free Access]
  32. Ford, K.A., Wammes, M., Neufeld, R.W.J., Mitchell, D.G., Théberge, J., Williamson, P.C., & E.A. Osuch. Unique functional abnormalities in youth with combined marijuana use and depression: an FMRI study.. Frontiers in Psychiatry 5(130): 1-11 (2014) - [Published | PMID: 25309462 | Free Access]
  33. Kluetsch, R., Ros, T., Théberge, J., Frewen, P.A., Calhoun, V.D., Schmahl, C., & R.A. Lanius. Plastic modulation of PTSD resting state networks and subjective wellbeing by EEG neurofeedback. Acta Psychiatr Scand 130(2): 123-136 (2014) - [Published | PMID: 24266644 | Free Access]
  34. Ford, K.A., Théberge, J., Neufeld, R.W.J., Williamson, P.C., & E.A. Osuch. Correlation of brain default mode network activation with bipolarity index in youth with mood disorders. J Affect Disord 150(3): 1174-1178 (2013) - [Published | PMID: 23806586]
  35. Ros, T., Théberge, J., Frewen, P.A., Kluetsch, R., Densmore, M., & R.A. Lanius. Mind over chatter: plastic up-regulation of the fMRI salience network directly after EEG neurofeedback. NeuroImage 65: 324-335 (2013) - [Published | PMID: 23022326]
  36. Marshall, H., Patrick, J., Prato, F.S., Butler, J., Théberge, J., Thompson, R.T., & R.Z. Stodilka. Description and Assessment of a Registration-Based Approach to Include Bones for Attenuation Correction of Whole-Body PET/MRI. Med Phys 40(8): 082509 (2013) - [Published | PMID: 23927354]
  37. Marshall, H., Prato, F.S., Deans, L., Théberge, J., Thompson, R.T., & R.Z. Stodilka. Variable lung density consideration in attenuation correction of whole-body PET/MRI. J Nucl Med 53(6): 977-984 (2012) - [Published | PMID: 22566600]
  38. Frewen, P.A., Brimson, M., & J. Théberge. Neuroimaging self-esteem: a fMRI study of individual differences in women. Soc Cog Affect Neurosci 8(5): 546-555 (2012) - [Published | PMID: 22403154]
  39. Järnum, H., Eskildsen, S.F., Steffensen, E.G., Lundbye-Christensen, S., Simonsen, C.W., Thomsen, I.S., Fründ, E.T., Théberge, J., & E.M. Larsson. Longitudinal MRI study of cortical thickness, perfusion, and metabolite levels in major depressive disorder. Acta Psychiatr Scand 124(6): 435-446 (2011) - [Published]
  40. Aoyama, N., Théberge, J., Drost, D., Manchanda, R., Northcott, S., Neufeld, R.W.J., Menon, R.S., Rajakumar, N., Pavlosky, W.F., Densmore, M., Schaefer, B., & P.C. Williamson. Grey matter and social functioning correlates of glutamatergic metabolite loss in schizophrenia. Br J Psychiatry 198(6): 448-456 (2011) - [Published | PMID: 21628707]
  41. Marshall, H., Stodilka, R.Z., Théberge, J., Sabondjian, E., Legros, A., Deans, L., Sykes, J., Thompson, R.T., & F.S. Prato. A comparison of MR-based attenuation correction in PET versus SPECT. Phys Med Biol 56(14): 4613-4629 (2011) - [Published | PMID: 21725141]
  42. Lanius, R.A., Bluhm, R.L., Coupland, N.J., Hegadoren, K.M., Rowe, B.H., Théberge, J., Neufeld, R.W.J., Williamson, P.C., & M. Brimson. Default mode network connectivity as a predictor of post-traumatic stress disorder symptom severity in acutely traumatized subjects. Acta Psychiatr Scand 121(1): 33-40 (2010) - [Published | PMID: 19426163 | Free Access]
  43. Robertson, J., Théberge, J., Weller, J., Drost, D., Prato, F.S., & A.W. Thomas. Low-frequency pulsed electromagnetic field exposure can alter neuroprocessing in humans. J R Soc Interface 7(44): 467-473 (2010) - [Published | PMID: 19656823 | Free Access]
  44. Robertson, J., Juen, N., Théberge, J., Weller, J., Drost, D., Prato, F.S., & A.W. Thomas. Evidence for a dose-dependent effect of pulsed magnetic fields on pain processing. Neurosci Lett 482(2): 160-162 (2010) - [Published | PMID: 20643187]
  45. Bluhm, R.L., Williamson, P.C., Osuch, E.A., Boksman, K., Neufeld, R.W.J., Théberge, J., & R.A. Lanius. Alterations in default network connectivity in posttraumatic stress disorder related to early-life trauma. J Psychiatry Neurosci 34(3): 187-194 (2009) - [Published | PMID: 19448848 | Free Access]
  46. Bluhm, R.L., Miller, J.E., Lanius, R.A., Osuch, E.A., Boksman, K., Neufeld, R.W.J., Théberge, J., Schaefer, B., & P.C. Williamson. Retrosplenial cortex connectivity in schizophrenia. Psychiatry Res 174(1): 17-23 (2009) - [Published | PMID: 19783410 | Free Access]
  47. Osuch, E.A., Bluhm, R.L., Williamson, P.C., Théberge, J., Densmore, M., & R.W.J. Neufeld. Brain activation to favorite music in healthy controls and depressed patients. Neuroreport 20(13): 1204-1208 (2009) - [Published | PMID: 19617860 | Free Access]
  48. Bluhm, R.L., Williamson, P.C., Lanius, R.A., Théberge, J., Densmore, M., Bartha, R., Neufeld, R.W.J., & E.A. Osuch. Resting state default-mode network connectivity in early depression using a seed region-of-interest analysis: Decreased connectivity with caudate nucleus. Psychiatry Clin Neurosci 63(6): 754-761 (2009) - [Published | Free Access]
  49. Théberge, J.. Perfusion magnetic resonance imaging in psychiatry. Top Magn Reson Imaging 19(2): 111-130 (2008) - [Published | PMID: 19363433 | Free Access]
  50. Musen, G., Simonson, D.C., Bolo, N.R., Driscoll, A., Weinger, K., Raji, A., Théberge, J., Renshaw, P.R., & A.M. Jacobson. Regional brain activation during hypoglycemia in type 1 diabetes. J Clin Endocrinol Metab 93(4): 1450-1457 (2008) - [Published | PMID: 18198228]
  51. Bluhm, R.L., Osuch, E.A., Lanius, R.A., Boksman, K., Neufeld, R.W.J., Théberge, J., & P.C. Williamson. Default mode network connectivity: effects of age, sex, and analytic approach. Neuroreport 19(8): 887-891 (2008) - [Published | PMID: 18463507 | Free Access]
  52. Bluhm, R.L., Miller, J.E., Lanius, R.A., Osuch, E.A., Boksman, K., Neufeld, R.W.J., Théberge, J., Schaefer, B., & P.C. Williamson. Spontaneous Low Frequency Fluctuations in the BOLD Signal in Schizophrenic Patients: Anomalies in the Default Network. Schizophrenia Bulletin 33: 1004-1012 (2007) - [Published | PMID: 17556752]
  53. Théberge, J., Williamson, K., Aoyama, N., Drost, D., Manchanda, R., Malla, A.K., Northcott, S., Menon, R.S., Neufeld, R.W.J., Rajakumar, N., Pavlosky, W.F., Densmore, M., Schaefer, B., & P.C. Williamson. Longitudinal grey-matter and glutamatergic losses in first-episode schizophrenia. Br J Psychiatry 191: 325-334 (2007) - [Published | PMID: 17906243 | Free Access]
  54. Théberge, J., Rowland, L.M., & J.E. Jensen. Comments regarding van Elst et al (2005): Increased Prefrontal and Hippocampal Glutamate Concentration in Schizophrenia: Evidence from a Magnetic Resonance Spectroscopy Study, Biol Psychiatry 58:724-730. Biol Psychiatry 61(10): 1218-1219 (2007) - [Published | PMID: 16950227 | Free Access]
  55. Théberge, J., & A. Jakary. Comment on "N-acetylaspartate reductions in the mediodorsal and anterior thalamus in men with schizophrenia verified by tissue volume corrected proton MRSI" (Schizophr Res 76, 173-185, 2005). Schizophr Res 81(1): 119-120 (2006) - [Published | PMID: 16298108]
  56. Théberge, J., Menon, R.S., Williamson, P.C., & D. Drost. Implementation issues of multivoxel STEAM-localized 1H spectroscopy. Magn Reson Med 53(3): 713-718 (2005) - [Published | PMID: 15723387]
  57. Boksman, K., Théberge, J., Williamson, P.C., Drost, D., Malla, A.K., Densmore, M., Takhar, J., Pavlosky, W.F., Menon, R.S., & R.W.J. Neufeld. A 4.0-T fMRI study of brain connectivity during word fluency in first-episode schizophrenia. Schizophr Res 75(2-3): 247-263 (2005) - [Published | PMID: 15885517]
  58. Théberge, J., Al-Semaan, Y., Jensen, J.E., Williamson, P.C., Neufeld, R.W.J., Menon, R.S., Schaefer, B., Densmore, M., & D. Drost. Comparative study of proton and phosphorus magnetic resonance spectroscopy in schizophrenia at 4 Tesla. Psychiatry Res 132(1): 33-39 (2004) - [Published | PMID: 15546701]
  59. Théberge, J., Al-Semaan, Y., Drost, D., Malla, A.K., Neufeld, R.W.J., Bartha, R., Manchanda, R., Menon, R.S., Densmore, M., Schaefer, B., & P.C. Williamson. Duration of untreated psychosis vs. N-acetylaspartate and choline in first episode schizophrenia: a 1H magnetic resonance spectroscopy study at 4.0 Tesla. Psychiatry Res 131(2): 107-114 (2004) - [Published | PMID: 15313517]
  60. Théberge, J., Al-Semaan, Y., Williamson, P.C., Menon, R.S., Neufeld, R.W.J., Rajakumar, N., Schaefer, B., Densmore, M., & D. Drost. Glutamate and glutamine in the anterior cingulate and thalamus of medicated patients with chronic schizophrenia and healthy comparison subjects measured with 4.0-T proton MRS. Am J Psychiatry 160(12): 2231-2233 (2003) - [Published | PMID: 14638596]
  61. Théberge, J., Bartha, R., Drost, D., Menon, R.S., Malla, A.K., Takhar, J., Neufeld, R.W.J., Rogers, J.M., Pavlosky, W.F., Schaefer, B., Densmore, M., Al-Semaan, Y., & P.C. Williamson. Glutamate and glutamine measured with 4.0 T proton MRS in never-treated patients with schizophrenia and healthy volunteers. Am J Psychiatry 159(11): 1944-1946 (2002) - [Published | PMID: 12411236 | Free Access]

Proceedings Articles

  1. Penner, J., Ford, K.A., Wammes, M., Neufeld, R.W.J., Mitchell, D.G., Théberge, J., Williamson, P.C., & E.A. Osuch. Neural circuitry underlying major depression and marijuana use: an emotion regulation fMRI task shows activation differences in dorsolateral and ventrolateral prefrontal cortex. (2015) - [Published]
  2. Gagnon, Y., Rajakumar, N., Gelman, N., Williamson, P.C., Drost, D., Théberge, J., & R. Nicolson. Investigating white matter abnormalities in autism using voxel-based relaxometry and voxel-based morphometry. (2010) - [Published]
  3. Robertson, J., Théberge, J., Weller, J., Drost, D., Prato, F.S., & A.W. Thomas. Functional imaging of magnetic field therapy. Proc. URSI (2008) - [Published]

Book Chapters

  1. Théberge, J.. Brain Protection in Schizophrenia, Mood and Cognitive Disorders. Ritsner, Michael S. ed., Springer, (2010)
  2. Taylor, R., Théberge, J., Williamson, P.C., Densmore, M., & R.W.J. Neufeld. Systems Factorial Technology - Model-driven Cognitive Neuroscience of Deviations in Stroop Performance in Schizophrenia. ()

Reports

  1. Stodilka, R.Z., Drost, D., Dubois, S.L., Lanius, R.A., Marshall, H., Théberge, J., & R.T. Thompson. Investigation of the Effects of Closed-Head Injury using Neurophysiological, Neuroimaging and Neurocognitive Assessment – *Phase 2, Task 1*. Lawson Health Research Institute (2008)
  2. Théberge, J., Lanius, R.A., St. Lawrence, K., Prato, F.S., Thompson, R.T., Thomas, A.W., & R.Z. Stodilka. Investigation of the Effects of Closed-Head Injury using Neurophysiological, Neuroimaging and Neurocognitive Assessment – *Phase 3, Task 1*. Lawson Health Research Institute (2008)
  3. Théberge, J., St. Lawrence, K., Thompson, R.T., Thomas, A.W., & R.Z. Stodilka. Investigation of the Effects of Closed-Head Injury using Neurophysiological, Neuroimaging and Neurocognitive Assessment – *Phase 3, Task 2*. Lawson Health Research Institute (2008)

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